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M9480623.TXT
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1994-08-20
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Document 0623
DOCN M9480623
TI Rhodococcus equi: first case in a heart transplant recipient.
DT 9410
AU Segovia J; Pulpon LA; Crespo MG; Daza R; Rodriguez JC; Rubio A; Serrano
S; Carreno MC; Varela A; Aranguena R; et al; Heart Transplant Unit,
Clinica Puerta de Hierro, Madrid, Spain.
SO J Heart Lung Transplant. 1994 Mar-Apr;13(2):332-5. Unique Identifier :
AIDSLINE MED/94304903
AB Rhodococcus equi is a gram-positive diphtheroid that occasionally
affects immunocompromised patients, usually causing a chronic
respiratory infection with cavitating pulmonary opacities on chest
radiograph that resemble mycobacterial or fungal disease. Etiologic
diagnosis presents a number of pitfalls, because Rhodococcus equi
isolates mimic many of the characteristics of other microorganisms more
familiar to the laboratory staff. The treatment of choice for this
disease has not yet been established, and its mortality rate is greater
than 50% in individuals with human immunodeficiency virus and 20% to 25%
among the remaining patients. We describe here the first case of
Rhodococcus equi infection in a heart transplant recipient. Clinical
presentation was typical, and treatment with a sensitivity-based
combination of antibiotics resulted in resolution of both the clinical
and radiologic picture.
DE Adult Antibiotics, Combined/THERAPEUTIC USE Case Report Heart
Transplantation/*IMMUNOLOGY Human Immunosuppressive
Agents/ADMINISTRATION & DOSAGE/ADVERSE EFFECTS Male Microbial
Sensitivity Tests Myocardial Diseases/IMMUNOLOGY/*SURGERY
Opportunistic Infections/DRUG THERAPY/*IMMUNOLOGY Pneumonia/*IMMUNOLOGY
Postoperative Complications/DRUG THERAPY/*IMMUNOLOGY Rhodococcus
equi/DRUG EFFECTS/*IMMUNOLOGY Septicemia/*IMMUNOLOGY JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).